FB2025_01 , released February 20, 2025
Allele: Dmel\bcd5
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General Information
Symbol
Dmel\bcd5
Species
D. melanogaster
Name
FlyBase ID
FBal0001079
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
Also Known As
bcd111, bcd111-3
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Frohnhofer and Nusslein-Volhard, 1987)
Mutagen
ethyl methanesulfonate
(Driever and Nusslein-Volhard, 1988, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Truncates the protein after amino acid 262.

(Dubnau and Struhl, 1996)

Stop codon at amino acid 257.

(Driever et al., 1989)

Amino acid replacement: Q262term.

(Struhl et al., 1989)

Nucleotide substitution: C2798T.

(Struhl et al., 1989)

2798 C --> T; 262 gln --> amber

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:6,757,889..6,757,889 [-]
Nucleotide change:

C6757889T

Reported nucleotide change:

C2798T

Amino acid change:

Q257term | bcd-PD; Q186term | bcd-PE; Q181term | bcd-PF; Q262term | bcd-PG

Reported amino acid change:

Q262term

(Struhl et al., 1989)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak bcd allele.

      (Driever and Nusslein-Volhard, 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (10)