FlyBase Allele Report: Dmel\MetRS-m[c00449]

General Information

Symbol

Dmel\MetRS-m^c00449

Species

D. melanogaster

Name

FlyBase ID

FBal0162844

Feature type

allele

Associated gene

Dmel\MetRS-m

Associated Insertion(s)

PBac{PB}MetRS-m^c00449

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Bloomington Drosophila Stock Center, 2004.11.6)

Progenitor genotype

Associated Insertion(s)

PBac{PB}MetRS-m^c00449

Cytology

Description

Allele components

Component

Use(s)

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:14,259,419..14,259,419 [+]

(Bloomington Drosophila Stock Center, 2004.11.6)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of neurodegenerative disease

CEA

(Bayat et al., 2012)

model of mitochondrial metabolism disease

CEA

(Bayat et al., 2012)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye photoreceptor cell | somatic clone | conditional

(Bayat et al., 2012)

Detailed Description

Statement

Reference

Photoreceptors in homozygous clones in the eye mostly appear normal in 1 day old flies, but show severe degeneration by 2 weeks of age.

(Bayat et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

MetRS-m^FB

(Bayat et al., 2012)

MetRS-m^HV

(Bayat et al., 2012)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

10077

w¹¹¹⁸; PBac{PB}MetRS-m^c00449/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Aats-met-m^c00449

Aats-met^c00449

(Bayat et al., 2012)

MetRS-m^c00449

(Bayat et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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