FB2025_01 , released February 20, 2025
Allele: Dmel\CchlJV32
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General Information
Symbol
Dmel\CchlJV32
Species
D. melanogaster
Name
FlyBase ID
FBal0194541
Feature type
allele
Associated gene
Dmel\Cchl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Liao et al., 2006)
Progenitor genotype
Cytology
Description

Nucleotide substitution at the last base pair of intron 2, which may affect splicing.

(Liao et al., 2006)

Nucleotide substitution: G?A.

(Liao et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:22,026,391..22,026,391 [-]
Nucleotide change:

G22026391A

Reported nucleotide change:

G?A

Comment:

G to A mutation at the last base of the second intron.

(Liao et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies containing homozygous eyes (induced using the eyFLP method) have a glossy-eye phenotype.

      Homozygous eye discs (induced by the eyFLP method) fail to incorporate BrdU properly, but have an essentially normal patterning of neuronal clusters emerging from the morphogenetic furrow (as assayed by elav expression).

      (Liao et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Cchlc04553

      (Liao et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that results in a "glossy-eye" phenotype in flies containing homozygous eyes (induced using the eyFLP method).

      (Liao et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CchlJV32
      JV32
      (Liao et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)