FB2025_01 , released February 20, 2025
Allele: Ecol\lexAVT003280.PU
Open Close
General Information
Symbol
Ecol\lexAVT003280.PU
Species
E. coli
Name
FlyBase ID
FBal0316910
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{VT003280-lexA.U}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Feng et al., 2014)
Progenitor genotype
Carried in construct
P{VT003280-lexA.U}
Cytology
Description

The 'VT003280' genomic fragment used in Scer\GAL4VT003280 regulates expression of a lexA::UnkAD driver.

(Feng et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
VT003280
Encoded product / tool
lexA::UnkAD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | female
      sensory neuron | subset of female reproductive system
      (Feng et al., 2014)
      adult stage
      adult sex peptide sensory neuron
      (Jang et al., 2017)
      Additional Information
      Statement
      Reference

      VT3280-LexA drives expression in SPR expressing sensory neurons (SPSN) in the female reproductive tract.

      (Feng et al., 2014)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Virgin females in which the Ecol\lexAVT003280-expressing neurons have been silenced are unable to mate. Elevated levels of egg laying are seen.

      Silencing Ecol\lexAVT003280-expressing neurons does not suppress the increased receptivity to males seen in mated females when SAG-1 neurons (Hsap\RELAAD.VT50405 and Scer\GAL4DBD.VT007068-expressing) have been activated.

      (Feng et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexAVT003280.PU
      Ecol\lexAVT003280
      Name Synonyms
      Secondary FlyBase IDs
        References (4)