FB2025_01 , released February 20, 2025
Allele: Hver\ω-ACTX-Hv1ahs.Tag:SS(Lsp1β)
Open Close
General Information
Symbol
Hver\ω-ACTX-Hv1ahs.Tag:SS(Lsp1β)
Species
H. versuta
Name
FlyBase ID
FBal0321244
Feature type
allele
Associated gene
Hver\ω-ACTX-Hv1a
Associated Insertion(s)
Carried in Construct
P{hs-ω-ACTX-Hv1a.T}
Transgenic product class
wild_type
(Tedford et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tedford et al., 2007)
Mutagen
in vitro construct
(Tedford et al., 2007)
Progenitor genotype
Carried in construct
P{hs-ω-ACTX-Hv1a.T}
Cytology
Description

An Hsp70 promoter drives expression of Hver\ω-ACTX-Hv1a which is tagged at the N-terminal end with a signal sequence (Tag:SS(Lsp1β)).

(Tedford et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Hver\ω-ACTX-Hv1a
Tagged with
Tag:SS(Lsp1β)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Zzzz\ω-ACTX-Hv1ahs.T:SS-Lsp1β using heat shock results in shaking, progressive loss of coordination, spastic paralysis and death of all individuals within 24-48 hours of heat shock.

      Young adults carrying Zzzz\ω-ACTX-Hv1ahs.T:SS-Lsp1β often fail to successfully inflate and harden their wings following eclosion.

      (Tedford et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hver\ω-ACTX-Hv1ahs.T:SS-Lsp1β
      Hver\ω-ACTX-Hv1ahs.Tag:SS(Lsp1β)
      Zzzz\ω-ACTX-Hv1ahs.T:SS-Lsp1β
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0320630
      • FBal0279422
      References (2)