FB2025_01 , released February 20, 2025
Allele: Dmel\Ir20a2
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General Information
Symbol
Dmel\Ir20a2
Species
D. melanogaster
Name
FlyBase ID
FBal0325469
Feature type
allele
Associated gene
Dmel\Ir20a
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Ganguly et al., 2017)
Progenitor genotype
Cytology
Description

Deletion which is predicted to result in a truncated protein product of 74 amino acid residues.

(Ganguly et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:21,478,844..21,478,845 [-]
Comment:

2 base deletion in Ir20a leads to early translation termination after 74 aa.

(Ganguly et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In a feeding preference assay for amino-acid-depleted yeast extract supplemented with serine, threonine and alanine, Ir20a2/Ir20a2 mutant females do not exhibit a significant change in preference index, as compared to controls.

      (Ganguly et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ir20a2
      (Ganguly et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)