FB2025_01 , released February 20, 2025
Allele: Dmel\Osi232
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General Information
Symbol
Dmel\Osi232
Species
D. melanogaster
Name
FlyBase ID
FBal0349207
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

2bp deletion between the two putative transmembrane sequences in Osi23.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

2bp deletion in Osi23 leads to a frameshift at amino acid 178 and early translation termination after the addition of seven novel amino acids.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Osi232 homozygotes show no visible defect in adult external morphology; the maxillary palp olfactory sensilla have significantly fewer nanopores, which is associated with severely reduced electrophysiological responses to both strong and weak odor stimuli, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Osi232
Name Synonyms
Secondary FlyBase IDs
    References (1)