FB2025_01 , released February 20, 2025
Allele: Dmel\Nil1
Open Close
General Information
Symbol
Dmel\Nil1
Species
D. melanogaster
Name
FlyBase ID
FBal0371750
Feature type
allele
Associated gene
Dmel\Nil
Associated Insertion(s)
TI{TI}Nil1
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Nandi et al., 2022)
Mutagen
CRISPR/Cas9
(Nandi et al., 2022)
Progenitor genotype
Associated Insertion(s)
TI{TI}Nil1
Cytology
Description

Replacement of the the majority of the conserved phosphatase domain of Nil with a DsRed marker.

(Nandi et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Nil1 third instar larval eye discs, antennal discs and fat bodies exhibit more autophagosomes/early autolysosomes (Atg8-puncta).

      (Nandi et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Nil1
      (Nandi et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)