FB2025_01 , released February 20, 2025
Allele: Dmel\Otud6C183R
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General Information
Symbol
Dmel\Otud6C183R
Species
D. melanogaster
Name
FlyBase ID
FBal0405272
Feature type
allele
Associated gene
Dmel\Otud6
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Villa et al., 2024)
gene targeting by homologous recombination
(Villa et al., 2024)
Progenitor genotype
Cytology
Description

Amino acid replacement: C183R.

(Villa et al., 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:15,504,267..15,504,267 [-]
Nucleotide change:

T15504267C

Reported nucleotide change:

T?C

Amino acid change:

C183R | Otud6-PA

Reported amino acid change:

C183R

Comment:

Cys183 is replaced with Arg in Otud6. A silent substitution (C to T) at codon H190 was also introduced.

(Villa et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Otud6G19995

      (Villa et al., 2024)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      OTUD6C183R
      (Villa et al., 2024)
      Otud6C183R
      Name Synonyms
      Secondary FlyBase IDs
        References (1)