FB2025_01 , released February 20, 2025
Gene Group: GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES
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General Information
Name
GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES
Species
D. melanogaster
Symbol
GPAT
FlyBase ID
FBgg0001061
Date last reviewed
2018-12-13
Number of members
3
Description
Description
Glycerol-3-phosphate O-acyltransferases are involved in the de novo synthesis of triacylglycerol (TAG) and glycerophospholipids, and thus are important for lipid storage/transport and membrane biogenesis. Specifically, they catalyze the first step in TAG synthesis, converting glycerol-3-phospate (G3P) to lysophosphatidic acid (LPA) by the transfer of a fatty acid from acyl-CoA. (Adapted from PMID:25415055.)
Notes on Group
Source Material
The GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES Gene Group has been compiled using the following publication(s): Toprak et al., 2020, Wilfling et al., 2013, and Kuhnlein, 2012 .
Key Gene Ontology (GO) terms
Molecular Function
glycerol-3-phosphate O-acyltransferase activity
Biological Process
triglyceride biosynthetic process
Cellular Component
endoplasmic reticulum
Enzymatic activity
Enzyme name (EC)
glycerol-3-phosphate 1-O-acyltransferase (2.3.1.15)
Related Gene Groups
Parent group(s)
NON-AMINOACYL ACYLTRANSFERASES
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG15450
GPAT
(Toprak et al., 2020, FlyBase, 2017-, Wilfling et al., 2013, Kuhnlein, 2012)
Gpat4
Glycerol-3-phosphate acyltransferase 4
GPAT
(Toprak et al., 2020, FlyBase, 2017-, Wilfling et al., 2013, Kuhnlein, 2012)
mino
minotaur
GPAT1, BcDNA:GH07066
(Toprak et al., 2020, Wilfling et al., 2013, Kuhnlein, 2012)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
GPAT
GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES
Secondary FlyBase ID(s)
References (5)