FlyBase Gene Report: Dhyd\thread

General Information

Symbol

Dhyd\thread

Species

D. hydei

Name

thread

Annotation Symbol

Feature Type

protein_coding_gene

FlyBase ID

FBgn0020731

Gene Model Status

Unannotated

Stock Availability

1 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

DhDhc7(Y), Threads, A

Summaries

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 26 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Dhyd\thread

Transgenic constructs containing regulatory region of Dhyd\thread

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Sterility

Allele

male fertile

male semi-fertile

Dhyd\thread^mut

male sterile | heat sensitive

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

gene

protein_coding_gene

(FlyBase curators, 2018-)

Stocks and Reagents

Stocks (1)

National Drosophila Species Stock Center

15085-1641.17

cn^A6237; thread^tu-p

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

The lampbrush loops 'Threads' and the 'DhDhc7(Y)' gene are one and the same transcription unit. The giant size of the Dhyd\thread gene as well as its appearance as a giant lampbrush loop are merely the result of transcription of huge clusters of satellite DNA within some of its 20 introns.

(Reugels et al., 2000)

Identification: PCR screen for Dynein heavy chain genes.

(Kurek et al., 1998)

Alterations in the morphology of the Threads lampbrush loops are faithful indicators of lareg deletions within the Dhyd\thread transcription unit.

(Kurek et al., 1996)

Y chromosome lampbrush loop genes.

(Hackstein and Hochstenbach, 1995)

Male fertility gene.

(Gatti and Pimpinelli, 1992)

Relationship to Other Genes

Source for database merge of

Source for merge of: Dhyd\thread Dhyd\Dhc7

(Kurek et al., 1999, Reugels et al., 1999)

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

(Hackstein and Hochstenbach, 1995, Hackstein et al., 1982)

D.hydei kl-5

(Carvalho, 2002)

DhDhc7

(Kurek et al., 1999)

DhDhc7(Y)

(Kurek et al., 2000, Reugels et al., 2000, Kurek et al., 1999, Reugels et al., 1999, Kurek et al., 1998)

Dhc-Yh3

(Reugels et al., 2000)

Dhc7

(Goldstein and Gunawardena, 2000)

Dhyd\A

Dhyd\Dhc7

Dhyd\ms(Y)A

Dhyd\thread

(Steinemann and Steinemann, 2000)

Threads

(Kurek et al., 1999, Reugels et al., 1999, Kurek et al., 1998, Kurek, 1997.10.27, Gatti and Pimpinelli, 1992)

ms(Y)A

(Hackstein et al., 1991)

thread

threads

(Hennig et al., 1989)

Name Synonyms

Dynein heavy chain 7

(Kurek et al., 1998)

gene A

(Hackstein and Hochstenbach, 1995)

thread

Secondary FlyBase IDs

FBgn0019100
FBgn0020163
FBgn0025429

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 21 )

Sequence Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF031494

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAC35745

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

O77075

Other crossreferences

InterPro - A database of protein families, domains and functional sites

References (21)

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