FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000096903
Interaction Network
Interactions Browser links
mth network
sun network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0179176-1a.CH.MS
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mth 

Mth

bait
sun 

sun

prey
sun 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
sun 
N-terminal region
sufficient binding region
aa 1-30
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as tagged protein in transfected HEK293 cells; prey produced from endogenous fly gene and obtained as HPLC fractions of whole fly extracts.

Both isoforms of sun can activate either isoform of mth.

Fractions of whole fly extract were tested for their ability to activate intracellular calcium changes in mth transfected HEK293 cells, but not untransfected cells. Purified active peptides were identified by mass spectrometry.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)