FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000112524
Interaction Network
Interactions Browser links
cdm network
tsu network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0209868-2.XC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
cdm 

Imp13

neutral component
cdm 

Imp13

neutral component
cdm 

Imp13

neutral component
tsu 

Y14

neutral component
tsu 

Y14

neutral component
tsu 

Y14

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced as a recombinant fusion proteins in bacterial system.

The crystal structure of a ternary complex containing cdm, tsu and mago was captured as 3 pairwise interactions.

FBrf0209868-4.PD.MW
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
cdm 

Imp13

bait

GST tag

cdm 
cdm 
tsu 

Y14

prey
tsu 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
cdm 
interaction domain
mutation disrupting interaction
aa 814,815

K814E,K815E

cdm 
interaction domain residue 447
mutation disrupting interaction
aa 447

Y447R

tsu 
interaction domain
sufficient binding region
aa 67-154
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)