FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cenp-C, baf
FlyBase ID
FBig0000120596
Interaction Network
Interactions Browser links
Cenp-C network
baf network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0246504-1.coIP.WB
Reference
Torras-Llort et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-ATCC
Participants
Corresponds to
Reported as
Role
Note
baf 

BAF

bait
Cenp-C 

CENP-C

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Torras-Llort et al., 2020)

The baf-Cenp-C interaction does not require the presence of DNA. It is decreased with overexpression of ball or flfl depletion and increased with ball depletion.

(Torras-Llort et al., 2020)
FBrf0246504-2.coIP.WB
Reference
Torras-Llort et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-ATCC
Participants
Corresponds to
Reported as
Role
Note
Cenp-C 

CENP-C

bait
baf 

BAF

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Torras-Llort et al., 2020)
FBrf0246504-3.coIP.WB
Reference
Torras-Llort et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-ATCC
Participants
Corresponds to
Reported as
Role
Note
baf 

BAF

bait
Cenp-C 

CENP-C

prey

GFP tag

Cenp-C 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Cenp-C 
FIM domain
mutation decreasing interaction
aa 1048-1066

FIM deletion, coordinates relative to Cenp-C-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from transfected construct, endogenous prey depleted.

(Torras-Llort et al., 2020)
External Crossreferences and Linkouts ( 0 )
References (1)