Harhangi, H.R., Sun, X., Wang, Y.X., Akhmanova, A., Miedema, K., Heyting, C., Hennig, W. (1999). RADHA - a new male germ line-specific chromosomal protein of Drosophila. Chromosoma 108(4): 235--242.
FlyBase ID
FBrf0111382
Publication Type
Research paper
Abstract
A new chromosomal protein - RADHA - of Drosophila is described that is specific for the male germ line. It is encoded by a single-copy gene, located in the region 96C-D of D. melanogaster polytene chromosomes. Transcription of the radha gene is restricted to the primary spermatocyte stage. The protein initially accumulates in some of the Y-chromosomal lampbrush loops. After meiosis it is found in the nuclei of spermatids and might be involved in chromatin rearrangement processes in the male germ line. RADHA is a basic protein with a C-terminal leucine zipper region and several segments capable of forming coiled-coil structures.
