Subject: mth error report
Hi,
..
mth:
AE003468; AAF47379
annotation of 1 splice site is a little wrong such that the translation
given by Celera is missing 1 amino acid (position 281, when comparing to
AF109308; AAD16981, Lin et al, Science  282:943-946 (1998))
CG17795, mth-like 2
AE003565; AAF50761
this translation is 482aa, Fig 3 of Brody T., Cravchik A., J. Cell Biol.
 150:F83-F88 (2000) show an extra C-terminal exon that translates:
IFPKQRAF SRSATQSTIE SISQTKRHFN MT
(80086-88 to 80173-175, exact positions I did not determine) which now
translates a 512 aa protein.
CG6530, mth-like 3
original 192aa protein (AE003803; AAF57863) has been replaced by 458aa
translation:
MRIVIGSFTA FLLLLLQNSN AEIPGCDFFD TVDISKAPRF SNGSYLYEGL LIPAHLTAEY
DYKLLADDSK EKVASHVRGC ACHLRPCIRF CCPQYQKMQK SKCYGDMSED ELNKHDPFVN
VTLSDGSVVR RHFKEDLIVQ SDLAKPGCPR MYFLNHELPM SIFTAIVISL ICIILTISVY
LYVEKLRNLH GKCFICYLAS LFLGYFFLVL NVWKYSSGFC VTAGFLGYFS VIAAFFWLSV
ISLTLWNSFS GNSSWLNRFL PQNRFLSYNL YAWGMALLLT AITYIADQVV KNEKLRPRVG
VGKNCWIYTG DMTVMIYFYG PMLLIIVFNI TMFVLTAFRI MKVKKEAQNF TQQQKTTNRL
NSDKQTYALF LRLFIIMGLS WSLEIISFLL SKNQAWAKAF MVADYFNWSQ GTVIFLLFVL
RPSTLKLLKE RIKGGRDEAG ASDEHISLQN TKIDPSVF
in same Fig as above (cannot remember how many exons were added, 3 or
4).
CG6536, mth-like 4
original 362 aa protein (AE003803; AAF57864) has an additional 12 aa at
the N-terminus and revised C-terminus so the translation is now 468aa:
MPKSNAEIPG CDFFDTVDIS KAPRFSNGSY LYEGLLIPAH LTAEYDYKLL ADDSKEKVAS
HVRGCACHLR PCIRFCCPQY QKMQKSKCYG DMSEDELNKH DPFVNVTLSD GSVVRRHFKE
DLIVQSDLAK PGCPRMYFLN HELPGNEFTL FENGSLLRHW DKVELSKREY CVQHLSFKDD
SIRIAPHFCP LSSEHSRTWK TVAIVISLIC IILTISVYLY VEKLRNLHGK CFICYLASLF
LGYFFLVLNV WKYSSGFCVT AGFLGYFSVM AAFFWLSVIG IHLRIKFSLA SNCLHRLLPE
NPFRAYNLYA WGIPLIMTAI TYTADQVVKN EKLRPRVGVG KNCWIYTGDM TVMIYFYGPM
LLLIAFNIIM FVLSAIYIYN IKKNVKGLVH KQQTNQQIND QQMFAIFLRL FILMGLSWSF
EILSFLLTKQ QAWARALMVA DYFNWSQGTI IFVLFILKPS ILKLIIAG
from same figure again (additional 2 exons).
CG16992, mth-like 6
current 172aa translation (AE003558; AAF50551) fails to encode any of
the 7 transmembrane required for a GPCR.
CG7476, mth-like 7
426aa translation (AE003556; AAF50475) has 5 of the 7 transmembrane
regions required for a GPCR, 2 C-terminal domains are missing.