FB2025_01 , released February 20, 2025
Allele: Dmel\dl16
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General Information
Symbol
Dmel\dl16
Species
D. melanogaster
Name
FlyBase ID
FBal0002658
Feature type
allele
Associated gene
Dmel\dl
Associated Insertion(s)
Carried in Construct
Also Known As
dl011
Key Links
Genomic Maps

Allele class

loss of function allele

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Lemaitre et al., 1995, Isoda et al., 1992)

loss of function allele

(Whalen and Steward, 1993)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Gln to stop codon substitution at amino acid 339, within the carboxy terminal group.

(Isoda et al., 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:17,439,271..17,439,271 [-]
Nucleotide change:

C17439271T

Amino acid change:

Q339term | dl-PA; Q339term | dl-PB; Q339term | dl-PD; Q339term | dl-PE

Reported amino acid change:

Q339term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Isoda et al., 1992)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When in trans with Df(2L)TW119 the transgene P{Dipt2.2-lacZ} is not induced.

      (Lemaitre et al., 1995)

      Strong dorsalization: loss of ventral epidermis.

      (Isoda et al., 1992)

      dominant

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dl011
      (Whalen and Steward, 1993, Isoda et al., 1992)
      dl16
      dlO11
      (Lemaitre et al., 1995, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)