FB2025_01 , released February 20, 2025
Allele: Dmel\ea3
Open Close
General Information
Symbol
Dmel\ea3
Species
D. melanogaster
Name
FlyBase ID
FBal0003457
Feature type
allele
Associated gene
Dmel\ea
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Chasan and Anderson, 1989)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The mean ln (natural logarithm) circulating hemocyte concentration (CHC) value of ea1/ea3 larvae is statistically indistinguishable from that of control siblings. The ability of ea1/ea3 larvae to encapsulate L.boulardi eggs is significantly reduced compared to that of control larvae.

      (Sorrentino et al., 2004)

      ea1/ea3 heterozygotes at 18oC have a weakly dorsalized phenotype: ventral denticle belts are of nearly normal width but there are abnormalities in the head skeleton.

      (Chasan and Anderson, 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ea3
      Name Synonyms
      Secondary FlyBase IDs
        References (5)