FB2025_01 , released February 20, 2025
Allele: Dmel\su(f)19
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General Information
Symbol
Dmel\su(f)19
Species
D. melanogaster
Name
FlyBase ID
FBal0016284
Feature type
allele
Associated gene
Dmel\su(f)
Associated Insertion(s)
Carried in Construct
Also Known As
su(f)L26
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Tudor et al., 1996)
Mutagen
X ray
(Tudor et al., 1996, Williams and O'Hare, 1996)
Progenitor genotype
Cytology
Description

Deletion of 8.5kb including the whole su(f) locus and 1.5kb of repeated DNA flanking the gene.

(Simonelig et al., 1996)

su(f) and the proximal copy of anon-k is deleted leaving the distal copy of anon-k.

(Tudor et al., 1996)

Deletion of entire su(f) region between the two 1.5kb repeats that flank the gene. Structure is essentially identical to that of su(f)414.

(Williams and O'Hare, 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      larval brain & mitotic cell cycle

      (Audibert and Simonelig, 1999)
      Detailed Description
      Statement
      Reference

      su(f)12/su(f)19 females shifted to the restrictive temperature as embryos die as first instar larvae. The number of metaphase mitotic figures in the brains of su(f)12/su(f)19 third instar larvae shifted to 29oC for 4 to 14 hours is double that of wild type.

      (Audibert and Simonelig, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      su(f)19 has lethal phenotype, non-suppressible by Scer\GAL4da.G32/Hsap\CSTF3UAS.cBa

      (Benoit et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      su(f)19 lethality is unaffected by Hsap\CSTF3Scer\UAS.cBa; Scer\GAL4da.G32.

      (Benoit et al., 2002)
      Complementation and Rescue Data
      Rescued by

      su(f)19 is rescued by su(f)UAS.cAa/Scer\GAL4da.G32

      (Benoit et al., 2002)
      Not rescued by

      su(f)19 is not rescued by su(f)G.lacZ

      (Audibert et al., 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lefevre.

      Comments
      Comments

      su(f)19, su(f)16-185, su(f)28, su(f)27, su(f)25 and su(f)3 exhibit the same pattern of complementation; fail to complement any su(f) allele. The allelic state of z has no effect on complementation behaviour.

      (Simonelig et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(1)L26
      su(f)19
      su(f)L26
      (Benoit et al., 2002, Audibert and Simonelig, 1999, Audibert and Simonelig, 1998, Audibert et al., 1998, Simonelig et al., 1996, Tudor et al., 1996, Williams and O'Hare, 1996)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0051073
      References (7)