FB2025_01 , released February 20, 2025
Allele: Dmel\bcdΔ
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General Information
Symbol
Dmel\bcdΔ
Species
D. melanogaster
Name
FlyBase ID
FBal0030595
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
P{bcdΔNRE}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Wharton and Struhl, 1991)
Progenitor genotype
Carried in construct
P{bcdΔNRE}
Cytology
Description

Construct: Deletion of 45bp containing bcd NRE (41bp downstream of the translation termination codon) from a 8.75kb EcoRI fragment that contains an entire and functional bcd transcription unit.

(Wharton and Struhl, 1991)
Allele components
Component
Use(s)
Encoded product / tool
bcd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      bcdΔ is a suppressor | maternal effect of embryonic thorax | anterior phenotype of hbΔ, nanosbcd.3UTR

      (Simpson-Brose et al., 1994)

      bcdΔ is a suppressor of embryo | posterior | ectopic phenotype of nanosbcd.3UTR

      (Simpson-Brose et al., 1994)

      bcdΔ is a suppressor of embryo | anterior phenotype of nanosbcd.3UTR

      (Simpson-Brose et al., 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The bicaudal phenotype of embryos from nosbcd.3UTR mothers is rescued by adding two maternal copies of bcdΔ, resulting in restored polarity, correct head development and rescued abdominal denticle patterning. The embryos still lack the anterior thorax (due to lowered levels of hb activity).

      (Simpson-Brose et al., 1994)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      B(Δ)
      (Wharton and Struhl, 1991)
      bcdΔ
      bcdΔ
      (Simpson-Brose et al., 1994)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)