FB2025_01 , released February 20, 2025
Allele: Dmel\sns1
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General Information
Symbol
Dmel\sns1
Species
D. melanogaster
Name
FlyBase ID
FBal0046369
Feature type
allele
Associated gene
Dmel\sns
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Paululat et al., 1995)
Mutagen
ethyl methanesulfonate
(Paululat et al., 1995)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dorsal vessel and visceral mesoderm is unaffected but major distortions occur in somatic mesoderm. Strong allele: Late stages of embryonic development show mostly unfused myoblasts. First distortions are visible during germ-band retraction. Unfused myoblasts are often arranged in specific locations where in the wild type ventral, pleural and longitudinal muscles form.

      (Paululat et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that shows lethality over the "rost30A" chromosome. The "rost30A" chromosome contains mutations in two genes: rost30A and sns43-49. sns1 has been shown to be allelic to sns43-49 rather than to rost30A.

      (Paululat et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      43-491
      rost1
      (Paululat et al., 1995)
      sns1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)