Imprecise excision of the P{lacW}pigeonP1 element, removing 5' regulatory sequences and the first exon of the drl gene and extending at least into P{lacW}pigeonP1.
After presentation of electric shock with a first odour, pigeon2, drl2 (Df(2R)lio2) mutant flies show a wild-type response to a second, different odour.
Homozygous flies carrying the pigeon2, drl2 chromosome (Df(2R)lio2) show a 60% decrease in 0.5 hour memory in a odour avoidance conditioning test.
Induced with: drl2.
Flies mutant for the pigeon2,drl2 (Df(2R)lio2) chromosome show a learning defect that may be more severe than that of flies mutant for pigeonP1,drlP1 mutants. Since the anatomical defect of the pigeon2,drl2 flies is more severe than for pigeonP1,drlP1 mutants, any lower learning score may be caused not by a mechanistic effect on learning but rather by an additional effect on the anatomy of mushroom bodies.