FlyBase Allele Report: Dmel\Prim2[T2]

General Information

Symbol

Dmel\Prim2^T2

Species

D. melanogaster

Name

FlyBase ID

FBal0103073

Feature type

allele

Associated gene

Dmel\Prim2

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Lukinova et al., 1999)

Progenitor genotype

Cytology

Description

Nucleotide substitution: G?A. Amino acid replacement: E138K.

(Chen et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:20,361,096..20,361,096 [-]

Nucleotide change:

G20361096A

Reported nucleotide change:

G?A

Amino acid change:

E138K | Prim2-PA

Reported amino acid change:

E138K

(Chen et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye | anterior (with Prim2^Sfaf240)

(Chen et al., 2000)

eye disc (with Prim2^Sfaf240)

(Chen et al., 2000)

mitotic cell cycle (with Prim2^Sfaf240)

(Chen et al., 2000)

Detailed Description

Statement

Reference

Cell death is seen in the anterior of the eye in DNAprim^T2/DNAprim^Sfaf240 late-stage pupae. More cells are in S phase at a given time compared to wild type in DNAprim^T2/DNAprim^Sfaf240 third larval instar eye discs.

(Chen et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Prim2^Sfaf240

(Chen et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

DNApol-α60^T2

DNAprim^T2

Prim2^T2

(Lukinova et al., 1999)

l(3)77ABe^T2

(Lukinova et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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