FlyBase Allele Report: Dmel\Mnn1[e30]

General Information

Symbol

Dmel\Mnn1^e30

Species

D. melanogaster

Name

FlyBase ID

FBal0198067

Feature type

allele

Associated gene

Dmel\Mnn1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Papaconstantinou et al., 2005)

Mutagen

P-element activity

(Papaconstantinou et al., 2005)

Progenitor genotype

P{EP}Mnn1^EP-GE11370

(Papaconstantinou et al., 2005)

Cytology

Description

Imprecise excision of the P{EP} element, resulting in a 2096bp deletion beginning at the site of the insertion in exon 1 and extending into exon 4 of the Mnn1 gene.

(Papaconstantinou et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Although Mnn1^e30 mutants are viable in control conditions, they show a high degree of lethality when subjected to heat shock, hypoxia, and oxidative stress. Mnn1^e30/Df(2L)spd^j2 show similar levels of lethality in response to heat shock.

(Papaconstantinou et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mnn1-e30

(Svetec et al., 2019)

Mnn1^-e30

(Svetec et al., 2019)

Mnn1^e30

(Papaconstantinou et al., 2010, Cerrato et al., 2006, Papaconstantinou et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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