FB2025_01 , released February 20, 2025
Allele: Dmel\Ada2bd272
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General Information
Symbol
Dmel\Ada2bd272
Species
D. melanogaster
Name
FlyBase ID
FBal0239943
Feature type
allele
Associated gene
Dmel\Ada2b
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Pankotai et al., 2005)
Progenitor genotype
P{EP}EP3412
(Pankotai et al., 2005)
Cytology
Description

Imprecise excision of the progenitor insertion has resulted in a 1500bp deletion, removing the promoter and extending into the second exon of Ada2b.

(Pankotai et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes and Ada2bd272/Df(3R)Ada2bd52 transheterozygotes show 77% lethality at the P5 pupal stage, and only 23% reach the pharate adult stage. No animals emerge as adults.

      (Pankotai et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ada2b<up> d272</up>
      (Fuse et al., 2022)
      Ada2bd272
      Name Synonyms
      Secondary FlyBase IDs
        References (2)