FB2025_01 , released February 20, 2025
Allele: Agos\CehW271L.UAS
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General Information
Symbol
Agos\CehW271L.UAS
Species
A. gossypii
Name
FlyBase ID
FBal0321342
Feature type
allele
Associated gene
Agos\Ceh
Associated Insertion(s)
Carried in Construct
P{UAS-AgEST.W271L}
Transgenic product class
missense_variant
(Cui et al., 2015)
Mutagen
    Nature of the Allele
    Transgenic product class
    missense_variant
    (Cui et al., 2015)
    Mutagen
    Progenitor genotype
    Carried in construct
    P{UAS-AgEST.W271L}
    Cytology
    Description

    UASt regulatory sequences drive expression of mutant Agos\Ceh carrying amino acid substitution W271L.

    (Cui et al., 2015)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    UASt
    Encoded product / tool
    Agos\Ceh
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Compared with wild-type, transgenic flies expressing Scer\GAL4tub.PU>Zzzz\CehW271L.Scer\UAS show higher resistance to insecticides chlorfenvinphos, malathion, parathion, monocrotophos, and deltamethrin.

        (Cui et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Agos\CehW271L.Scer\UAS
        Agos\CehW271L.UAS
        Zzzz\CehW271L.Scer\UAS
        Name Synonyms
        Secondary FlyBase IDs
        • FBal0320728
        • FBal0314185
        References (2)