FB2025_01 , released February 20, 2025
Allele: Dmel\VincHead-ΔD1-mito.UASp.TagRFP
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General Information
Symbol
Dmel\VincHead-ΔD1-mito.UASp.TagRFP
Species
D. melanogaster
Name
FlyBase ID
FBal0325497
Feature type
allele
Associated gene
Dmel\Vinc
Associated Insertion(s)
Carried in Construct
M{UASp-Vinc.Head-ΔD1-mito.TagRFP}
Key Links
Transgenic product class
inframe_deletion
(Maartens et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Maartens et al., 2016)
Mutagen
in vitro construct
(Maartens et al., 2016)
Progenitor genotype
Carried in construct
M{UASp-Vinc.Head-ΔD1-mito.TagRFP}
Cytology
Description

UASp regulatory sequences drive expression of the Vinc head domain lacking the D1 region (Vinc amino acid residues 257-724 are present). The protein is targeted to the mitochondria using a C-terminal Tag:Mito(actA) membrane anchor and is also tagged at the C-terminal end with TagRFP.

(Maartens et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Vinc
Tagged with
Tag:Mito(actA)
TagRFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of VincHead-ΔD1-mito.Scer\UAS.P\T.T:Equa\eqFP578-TagRFP under the control of Scer\GAL4Mef2.PU leads to no embryonic muscle defects, as compared to controls; expression under the control of Scer\GAL4Mef2.PU also does not lead to the formation of ectopic VincHead-ΔD1-mito.Scer\UAS.P\T.T:Equa\eqFP578-TagRFP-positive cytoplasmic protein aggregates in embryonic muscles, as compared to controls.

      (Maartens et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      VincHead-Δ1-mito.Scer\UAS.P\T.T:Equa\eqFP578-TagRFP
      VincHead-ΔD1-mito.Scer\UAS.P\T.T:Equa\eqFP578-TagRFP
      VincHead-ΔD1-mito.UASp.TagRFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)