FB2025_01 , released February 20, 2025
Allele: Dmel\Idh3b+t3.0
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General Information
Symbol
Dmel\Idh3b+t3.0
Species
D. melanogaster
Name
FlyBase ID
FBal0325704
Feature type
allele
Associated gene
Dmel\Idh3b
Associated Insertion(s)
Carried in Construct
M{Idh3b.3.0}
Key Links
Transgenic product class
wild_type
(Duncan et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Duncan et al., 2017)
Mutagen
in vitro construct
(Duncan et al., 2017)
Progenitor genotype
Carried in construct
M{Idh3b.3.0}
Cytology
Description

3.0kb wild-type genomic fragment containing Idh3b. Contains the entire A isoform plus 198bp of upstream sequence.

(Duncan et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
Idh3b
Idh3b_Idh3b-rescue
Encoded product / tool
Idh3b
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Idh3b+t3.0 rescues Idh3b2/Df(3R)Exel6188

      (Duncan et al., 2017)

      Idh3b+t3.0 rescues Idh3b3/Df(3R)Exel6188

      (Duncan et al., 2017)

      Idh3b+t3.0 rescues Idh3b1/Df(3R)Exel6188

      (Duncan et al., 2017)
      Comments

      The lethality of Idh3b1/Df(3R)Exel6188, Idh3b2/Df(3R)Exel6188 and Idh3b3/Df(3R)Exel6188 transheterozygous mutants is rescued by combination with a single copy of Idh3b+t3.0 as viable adults are recovered and the abnormal persistence of larval salivary gland characteristic for Idh3b mutants is not observed in the Idh3b2/Df(3R)Exel6188; Idh3b+t3.0 rescue pupae.

      (Duncan et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Idh3b+t3.0
      Name Synonyms
      Secondary FlyBase IDs
        References (2)