FB2025_01 , released February 20, 2025
Allele: Ecol\lacZHsp83.orb.NH
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General Information
Symbol
Ecol\lacZHsp83.orb.NH
Species
E. coli
Name
FlyBase ID
FBal0340277
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Hsp83-lacZ-orb3'UTR.NH}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lantz and Schedl, 1994)
Progenitor genotype
Ecol\lacZHsp83.Adh
(Lantz and Schedl, 1994)
Carried in construct
P{Hsp83-lacZ-orb3'UTR.NH}
Cytology
Description

815bp HindIII-NdeI fragment of the orb 3' UTR (lacking 200bp from the 3' end) is fused downstream of Ecol\lacZ in reverse orientation.

(Lantz and Schedl, 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp83
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Between 3 and 6% of eggs produced by females carrying orbNH.Hsp83.T:Ecol\lacZ have ventralised chorions. 23-45% of eggs produced by orbF343/+ females carrying one copy of orbNH.Hsp83.T:Ecol\lacZ have ventralised chorions (depending on the orbNH.Hsp83.T:Ecol\lacZ line used).

      (Tan et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      orbNH.Hsp83.T:Ecol\lacZ acts as a dominant negative allele.

      (Tan et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Ecol\lacZHsp83.orb.NH
      Ecol\lacZorb.NH.Hsp83
      lacZorb.NH.Hsp83
      orbNH.Hsp83.T:Ecol\lacZ
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0056616
      • FBal0340243
      References (3)