GC9990999CG
A154R | TER94-PA; A179R | TER94-PC; A112R | TER94-PD; A179R | TER94-PE
A154R
Analogous G157R mutation in human VCP implicated in FTDALS6 and/or IBMPFD1 (MSP-1) disease; mutation carried on in vitro construct; site of nucleotide substitution in fly gene inferred by FlyBase curator based on reported amino acid change.
TER94A154R.sfGFP heterozygotes show a progressive decrease in climbing ability in males only. Their larval body wall muscles are disorganized and show lysosomal defects.