FB2025_01 , released February 20, 2025
Allele: Dmel\sloth2+tBa
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General Information
Symbol
Dmel\sloth2+tBa
Species
D. melanogaster
Name
FlyBase ID
FBal0386643
Feature type
allele
Associated gene
Dmel\sloth2
Associated Insertion(s)
Carried in Construct
P{Δsloth1.sloth2}
Key Links
Transgenic product class
genomic_DNA
(Bosch et al., 2022)
wild_type
(Bosch et al., 2022)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Bosch et al., 2022)
wild_type
(Bosch et al., 2022)
Mutagen
in vitro construct
(Bosch et al., 2022)
Progenitor genotype
Carried in construct
P{Δsloth1.sloth2}
Cytology
Description

A genomic rescue transgene comprising the sloth1-sloth2 region in which the sloth1 ORF is deleted.

(Bosch et al., 2022)
Allele components
Component
Use(s)
Regulatory region(s)
sloth1
sloth2
Encoded product / tool
sloth2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      sloth2+tBa is a non-suppressor of lethal | male phenotype of sloth1KO

      (Bosch et al., 2022)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      sloth2+tBa rescues sloth2KO

      (Bosch et al., 2022)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sloth2+tBa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)