FB2025_01 , released February 20, 2025
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Adar, Fmr1
FlyBase ID
FBig0000095893
Interaction Network
Interactions Browser links
Adar network
Fmr1 network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0216747-1.TAP.MS
Reference
Bhogal et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Fmr1 

dFMR1

bait

TAP pull down

Adar 

dADAR

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line transfected with tagged Fmr1 construct.

(Bhogal et al., 2011)
FBrf0216747-2.TAP.WB
Reference
Bhogal et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Adar 

dADAR

bait

TAP pull down

Fmr1 

dFMR1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line transfected with tagged Adar constructs.

(Bhogal et al., 2011)

No change was observed when lysate was treated with RNase A prior to pulldown.

(Bhogal et al., 2011)

Two isoforms of the Adar protein were assayed: Adar(3A) = FlyBase Adar-PN and Adar(3/4) = FlyBase Adar-PA; no differences were observed.

(Bhogal et al., 2011)
FBrf0216747-3.coIP.WB
Reference
Bhogal et al., 2011
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Adar 

dADAR

bait

HA tag

Fmr1 

dFMR1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads from transgenic lines carrying tagged Adar constructs.

(Bhogal et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)