Interaction in vitro; proteins produced as a recombinant fusion protein in bacterial system.

Drep-3 inhibits the nuclease activity of Drep-2 in vitro.

Interaction in vitro; proteins produced as a recombinant fusion protein in bacterial system.

Drep-3 inhibits the nuclease activity of Drep-2 in vitro.

Interaction in vitro; proteins produced as a recombinant fusion protein in bacterial system.

The presence of Drep-3 prevents Drep-2 homooligomerization.

The Drep-2 K40E mutation disrupts binding of Drep-3, but not Drep-2 homooligomerization.

Only interactions absent in negative controls (wildtype lysate or no antibody) at FDR = 1% are reported.

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

Interaction in vitro; proteins produced as a recombinant fusion proteins in bacterial system.

Estimated molecular weight is consistent with a heterodimer.