FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
polybromo, Rel
FlyBase ID
FBig0000108949
Interaction Network
Interactions Browser links
polybromo network
Rel network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0235292-1.coIP.WB
Reference
He et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2[star]
Participants
Corresponds to
Reported as
Role
Note
polybromo 

polybromo

bait

FLAG tag

Rel 

Rel

prey

GFP tag

Rel 
Rel 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Rel 
interaction domain
sufficient binding region
aa 1-545

coordinates relative to Rel-PA

Rel 
phosphorylation sites
mutation disrupting interaction
aa 528-529

S528A,S529A, coordinates relative to Rel-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(He et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)