FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Nab2, Fmr1
FlyBase ID
FBig0000111519
Interaction Network
Interactions Browser links
Nab2 network
Fmr1 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0236325-1.coIP.WB
Reference
Bienkowski et al., 2017
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Nab2 

dNab2

bait

FLAG tag

Fmr1 

dFMRP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Bienkowski et al., 2017)

The Nab2-Fmr1 interaction is resistant to RNase treatment and is found in both nuclear and cytoplasmic fractions.

(Bienkowski et al., 2017)
FBrf0252576-2.coIP.WB
Reference
Rounds et al., 2022
Description
physical association
Assay
Collection
Source/Stage
adult head / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Nab2 

Nab2

bait

Flag tag

Fmr1 

Fmr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Rounds et al., 2022)

Positive control

(Rounds et al., 2022)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)