FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
CoRest, l(3)mbt
FlyBase ID
FBig0000114681
Interaction Network
Interactions Browser links
CoRest network
l(3)mbt network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0218194-24.CH.WB
Reference
Meier et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc
Participants
Corresponds to
Reported as
Role
Note
CoRest 

dCoRest

unspecified role
CoRest 

dCoRest

unspecified role
CoRest 

dCoRest

unspecified role
l(3)mbt 

dL(3)mbt

unspecified role
l(3)mbt 

dL(3)mbt

unspecified role
l(3)mbt 

dL(3)mbt

unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of Kc cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Meier et al., 2012)

CoRest fractionates in two peaks suggesting two CoRest containing complexes. CoRest co-fractionates with l(3)mbt in one peak.

(Meier et al., 2012)
FBrf0244272-1.CH.WB
Reference
Mačinković et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-B2
Participants
Corresponds to
Reported as
Role
Note
CoRest 

dCoREST

neutral component
CoRest 

dCoREST

neutral component
CoRest 

dCoREST

neutral component
l(3)mbt 

dL(3)mbt

neutral component
l(3)mbt 

dL(3)mbt

neutral component
l(3)mbt 

dL(3)mbt

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nclear extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mačinković et al., 2019)
FBrf0244272-13.coIP.WB
Reference
Mačinković et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-B2
Participants
Corresponds to
Reported as
Role
Note
CoRest 

dCoREST

bait

GFP tag

l(3)mbt 

dL(3)mbt

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from tagged endogenous gene; prey produced from endogenous gene.

(Mačinković et al., 2019)
FBrf0244272-18.coIP.MS
Reference
Mačinković et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-B2
Participants
Corresponds to
Reported as
Role
Note
CoRest 

dCoREST

bait

FLAG tag

l(3)mbt 

dL(3)mbt

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from transfected construct or endogenous gene; prey produced from endogenous gene.

(Mačinković et al., 2019)
FBrf0244272-5.coIP.WB
Reference
Mačinković et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-B2
Participants
Corresponds to
Reported as
Role
Note
CoRest 

dCoREST

bait

FLAG tag

l(3)mbt 

dL(3)mbt

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Mačinković et al., 2019)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)