FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Hsap\SNCA, Lsd-2
FlyBase ID
FBig0000121476
Interaction Network
Interactions Browser links
Hsap\SNCA network
Lsd-2 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0252011-1.CL.FM
Reference
Girard et al., 2021
Description
physical association
Assay
Collection
Source/Stage
retina / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hsap\SNCA 

αSyn

bait

fused to outer mitochondrial membrane anchor

Lsd-2 

dPlin2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was whole mount adult retinas; bait produced from transgenic construct; prey produced from tagged transgenic construct.

(Girard et al., 2021)

Bait and prey proteins were driven by Rh1-GAL4, a photoreceptor neuron-specific driver. The colocalization of both proteins to lipid droplet surfaces was taken as evidence of direct physical interaction.

(Girard et al., 2021)
External Crossreferences and Linkouts ( 0 )
References (1)