FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000122023
Interaction Network
Interactions Browser links
ci network
Sumo network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0232304-2.PD.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
ci 

Ci

bait

GST tag

ci 
ci 
ci 
ci 
ci 
Sumo 

SUMO

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
ci 
N-terminal-1 domain
sufficient binding region
aa 1-404
ci 
N-terminal-2 domain
sufficient binding region
aa 405-707
ci 
C-terminal-1 domain
sufficient binding region
aa 705-824
ci 
C-terminal domain residue 782
mutation decreasing interaction
aa 782

K782R within the context of aa 701-1397.

ci 
N-terminal domain K residues
mutation decreasing interaction
aa 351, 360, 364, 535, 545, 561, 611, 614

K to R mutations within the context of aa 1-700.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as recombinant fusion proteins in bacterial system.

External Crossreferences and Linkouts ( 0 )
References (1)