FB2025_01 , released February 20, 2025
Allele: Dmel\fu40
Open Close
General Information
Symbol
Dmel\fu40
Species
D. melanogaster
Name
FlyBase ID
FBal0004873
Feature type
allele
Associated gene
Dmel\fu
Associated Insertion(s)
Carried in Construct
Also Known As
fu9P2.3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Preat et al., 1993, Eberl et al., 1992)
Progenitor genotype
Cytology
Description

Class I fu allele, affects the catalytic domain but does not change the open reading frame.

(Preat et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Germline clone analysis demonstrate maternal effect causing abnormal oogenesis.

      (Eberl et al., 1992)

      fu40/Y sons of fu40/+ mothers die as late pupae or newly emerged adults; lethality suppressible by Su(fu). fu embryos produced by homozygous germ-line clones are mostly lethal (70%); those that hatch mostly achieve adulthood (Perrimon and Mahowald, 1987). pupal lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      fu40 has phenotype, suppressible by Su(fu)LP

      (Preat et al., 1993)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When in combination with Su(fu)LP heterozygotes individuals display a partially suppressed fu phenotype.

      (Preat et al., 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Perrimon.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      fu40
      fu9P2.3
      (Eberl et al., 1992, Busson et al., 1988)
      fu9P2
      (Preat et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)