FB2025_01 , released February 20, 2025
Allele: Dmel\gl1
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General Information
Symbol
Dmel\gl1
Species
D. melanogaster
Name
FlyBase ID
FBal0005040
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

photoreceptor cell & axon

Detailed Description
Statement
Reference

In contrast to wild-type, gl1 mutants fail to exhibit any light-dependent temperature preference.

Wild-type larvae reduce their path lengths when exposed to light. This response is severely reduced in gl1 larvae. Wild-type larvae show increased head swinging when exposed to light. This response is abolished in gl1 larvae. Wild-type larvae show a greater change in direction when lights are turned on or off (light (L) to dark (D), or D to L transition) than in the absence of a light transition (D to D). The amplitude of change of direction is greater for the D to L than for the L to D transition. This difference in the amplitude of change of direction between the D to L and L to D transitions is abolished in gl1 larvae, although change of direction in the absence of a light transition (D to D) is still significantly lower than for either the D to L and L to D transition.

Newly fertilised homozygous females elicit as much courtship from wild-type males as do newly fertilised wild-type females. Newly fertilised homozygous females extrude their ovipositors at a much lower frequency than control females.

Displays locomotor activity rhythm with an approximately 24h period.

Photoreceptor axons project to the brain aberrantly in late third instar larvae. This phenotype is variable. There is a variable pattern of S phase cells located between the outer proliferative centre and inner proliferative centre, in the region where the lamina precursor cells normally reside.

strength: moderate

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

gl[+]/gl1 is an enhancer of visible | heat sensitive phenotype of peb1

Phenotype Manifest In
Enhancer of
Statement
Reference

gl[+]/gl1 is an enhancer of eye | heat sensitive phenotype of peb1

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (8)
Notes on Origin
Discoverer

Muller, Feb. 1918.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (20)