FB2025_01 , released February 20, 2025
Allele: Dmel\prd10
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General Information
Symbol
Dmel\prd10
Species
D. melanogaster
Name
FlyBase ID
FBal0013973
Feature type
allele
Associated gene
Dmel\prd
Associated Insertion(s)
Carried in Construct
Also Known As
prdIIN
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Mutation is predicted to result in a truncated lacking the last 126 amino acids of wild-type prd.

(Bertuccioli et al., 1996)

Amino acid replacement: T406A.

(Bertuccioli et al., 1996)

Amino acid replacement: Q487term.

(Bertuccioli et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:12,083,940..12,083,940 [-]
Nucleotide change:

A12083940G

Amino acid change:

T383A | prd-PA; T406A | prd-PB

Reported amino acid change:

T406A

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Bertuccioli et al., 1996)
point_mutation
2L:12,083,697..12,083,697 [-]
Nucleotide change:

C12083697T

Amino acid change:

Q464term | prd-PA; Q487term | prd-PB

Reported amino acid change:

Q487term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Bertuccioli et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Weak allele.

      (Bertuccioli et al., 1996)

      The phenotype of odd5 prd10 double homozygotes is more limited than simple additivity of the two phenotypes.

      (Coulter and Wieschaus, 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Interacts with RpII140wimp maternal effect.

      (Parkhurst and Ish-Horowicz, 1991)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      prd10
      prdIIN27
      (Parkhurst and Ish-Horowicz, 1991)
      prdIIN
      (Xue et al., 2001, Bertuccioli et al., 1996, Coulter and Wieschaus, 1988, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)