FB2025_01 , released February 20, 2025
Allele: Dmel\nulloUAS.Tag:HA
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General Information
Symbol
Dmel\nulloUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0129179
Feature type
allele
Associated gene
Dmel\nullo
Associated Insertion(s)
Carried in Construct
P{UAS-nullo.HA}
Key Links
Transgenic product class
wild_type
(Hunter et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hunter et al., 2002)
Mutagen
in vitro construct
(Hunter et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-nullo.HA}
Cytology
Description

UASt regulatory sequences drive expression of nullo tagged with Tag:HA.

(Hunter et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
nullo
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nulloScer\UAS.T:Ivir\HA1, under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16, results in severe embryonic cellularisation defects. Expression of nulloScer\UAS.T:Ivir\HA1, under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16, results in cells that are unable to flatten or constrict their apical surfaces.

      (Dawes-Hoang et al., 2005)

      Expression of nulloScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 causes lethality in 87% of embryos and blocks the formation of apical junctions.

      (Hunter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of nulloScer\UAS.T:Ivir\HA1, under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16 in an arm043A01 mutant, results in cells that are unable to flatten or constrict their apical surfaces as in nulloScer\UAS.T:Ivir\HA1 (Scer\GAL4mat.αTub67C.T:Hsim\VP16) single mutants.

      (Dawes-Hoang et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nulloScer\UAS.T:Ivir\HA1
      nulloUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (3)