FlyBase Allele Report: Dmel\lqf[L71]

General Information

Symbol

Dmel\lqf^L71

Species

D. melanogaster

Name

FlyBase ID

FBal0147029

Feature type

allele

Associated gene

Dmel\lqf

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Nucleotide substitution: G?A.

(Overstreet et al., 2003)

Amino acid replacement: W73term.

(Overstreet et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:7,533,656..7,533,656 [+]

Nucleotide change:

G7533656A

Reported nucleotide change:

G?A

Amino acid change:

Reported amino acid change:

W73term

(Overstreet et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage (with lqf^ARI)

(Xie et al., 2012)

some die during embryonic stage (with lqf^ARI)

(Xie et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

lqf^L71/lqf^ARI is rescued by lqf^FL.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔCBM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔDPW.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔNPF.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^{ΔCBM.ΔDPW1.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ENTH.TD.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^{ENTH.FTVF.RDAA.GFP}

(Xie et al., 2012)

lqf^L71 is rescued by lqf^{ENTH.ro.Tag:FLAG}

(Overstreet et al., 2003)

Partially rescued by

lqf^L71/lqf^ARI is partially rescued by lqf^ΔENTH.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ΔUIM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ΔUIM2.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^{UIM1.EA.ΔUIM2.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^UIM1.EA.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^{ΔCBM.ΔDPW.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^4xNPF.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ENTH.RA.GFP

(Xie et al., 2012)

Not rescued by

lqf^L71/lqf^ARI is not rescued by lqf^ENTH.UIM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is not rescued by lqf^{ENTH.RWRK.AAAA.GFP}

(Xie et al., 2012)

Comments

lqf^ARI/lqf^L71 animals carrying lqf^{ΔENTH.T:Avic\GFP} are semi-viable and have a slight rough eye phenotype.

lqf^ARI/lqf^L71 animals carrying lqf^{ΔUIM.T:Avic\GFP} die as pupae.

lqf^{ΔUIM2.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (97 +/- 3% of facets in the eye are normal).

lqf^ARI/lqf^L71 animals carrying lqf^{UIM1.EA.ΔUIM2.T:Avic\GFP} die as pupae.

lqf^{UIM1.EA.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (68 +/- 12% of facets in the eye are normal).

lqf^{ΔCBM.ΔDPW.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (92 +/- 2% of facets in the eye are normal).

lqf^ARI/lqf^L71 animals carrying lqf^{4xNPF.T:Avic\GFP} are semi-viable and have slight eye defects.

lqf^{ENTH.RA.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (64 +/- 14% of facets in the eye are normal).

(Xie et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

90936

lqf^L71 P{neoFRT}80B/TM3, Sb¹

Notes on Origin

Discoverer

Comments

Allelic series based on viability: lqf^FDD9 < lqf^bE248 < lqf^S011027 < lqf^BT < lqf^ARI = lqf^L895 = lqf^L71.

(Overstreet et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

L71

(Overstreet et al., 2003)

lqf^L71

(Troost et al., 2023, Berndt et al., 2017, Xie et al., 2012, Csikós et al., 2009, Eun et al., 2008, Jaekel and Klein, 2006)

lqf^l71

(Vaccari et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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