FB2025_01 , released February 20, 2025
Allele: Dmel\Oatp58DbRNAi.UAS
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General Information
Symbol
Dmel\Oatp58DbRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0182445
Feature type
allele
Associated gene
Dmel\Oatp58Db
Associated Insertion(s)
Carried in Construct
P{UAS-Oatp58Db.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Torrie et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Torrie et al., 2004)
Mutagen
in vitro construct
(Torrie et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Oatp58Db.RNAi}
Cytology
Description

UASt sequences control expression of hairpin loop consisting of an inverted repeat of 283bp from the coding region of Oatp58Db, separated by a 501bp spacer.

(Torrie et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Oatp58Db
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Active transport of Oabain across the Malpighian tubule is significantly decreased in Malpighian tubules dissected from Oatp58DbdsRNA.Scer\UAS; Scer\GAL4c42 adults compared to those dissected from wild-type, Scer\GAL4c42 or Oatp58DbdsRNA.Scer\UAS adults.

      (Torrie et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      dsRNA expression from the transgene has been used to study the phenotypic consequences of dsRNA interference (RNAi) of the Oatp58Db gene.

      (Torrie et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Oatp58DbRNAi.UAS
      Oatp58DbdsRNA.Scer\UAS
      Oatp58DbdsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)