FlyBase Allele Report: Dmel\DCP2[e00034]

General Information

Symbol

Dmel\DCP2^e00034

Species

D. melanogaster

Name

FlyBase ID

FBal0185284

Feature type

allele

Associated gene

Dmel\DCP2

Associated Insertion(s)

PBac{RB}DCP2^e00034

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Gene Disruption Project members and Exelixis, 2005)

Progenitor genotype

Associated Insertion(s)

PBac{RB}DCP2^e00034

Cytology

Description

Allele components

Component

Use(s)

Inserted element

PBac{RB}

gene trap

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:15,825,923..15,825,923 [+]

(Kunar and Roy, 2021, Mishra et al., 2020, Pressman et al., 2012, Gene Disruption Project members and Exelixis, 2005)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate (with DCP2^BG01766)

(Mishra et al., 2020)

abnormal developmental rate (with DCP2^tb)

(Mishra et al., 2020)

chemical resistant | adult stage (with DCP2^c02419)

(Ren et al., 2012)

increased cell number | larval stage (with DCP2^tb)

(Mishra et al., 2020)

increased occurrence of cell division | larval stage (with DCP2^tb)

(Mishra et al., 2020)

lethal | recessive

(Ren et al., 2012)

lethal - all die during P-stage (with DCP2^BG01766)

(Mishra et al., 2020)

lethal - all die during P-stage (with DCP2^tb)

(Mishra et al., 2020)

Phenotype Manifest In

larval brain | larval stage (with DCP2^tb)

(Mishra et al., 2020)

larval neuroblast | increased number (with DCP2^tb)

(Mishra et al., 2020)

wing disc | larval stage (with DCP2^tb)

(Mishra et al., 2020)

Detailed Description

Statement

Reference

DCP2^tb/DCP2^e00034 larval brains exhibit increased occurrence of cell division.

(Mishra et al., 2020)

DCP2^e00034/DCP2^e00034, but not DCP2^e00034/+, mutants are lethal.

DCP2^c02419/DCP2^e00034, but not DCP2^e00034/+ mutants, are resistant to chronic nicotine-induced locomotor hyperactivity.

(Ren et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

DCP2^tb

(Mishra et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

85518

w¹¹¹⁸; PBac{RB}DCP2^e00034/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG6169^e00034

DCP2^e00034

(Kunar and Roy, 2021)

Dcp2^e00034

(Pressman et al., 2012, Ren et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close