FB2025_01 , released February 20, 2025
Allele: Dmel\Rab10Q68L.UASp.YFP
Open Close
General Information
Symbol
Dmel\Rab10Q68L.UASp.YFP
Species
D. melanogaster
Name
FlyBase ID
FBal0215409
Feature type
allele
Associated gene
Dmel\Rab10
Associated Insertion(s)
Carried in Construct
P{UASp-YFP.Rab10.Q68L}
Key Links
Transgenic product class
missense_variant
(Zhang et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Zhang et al., 2007)
Mutagen
in vitro construct
(Zhang et al., 2007, Zhang et al., 2007)
Progenitor genotype
Carried in construct
P{UASp-YFP.Rab10.Q68L}
Cytology
Description

Amino acid replacement: Q68L.

(Zhang et al., 2007)

UASp regulatory sequences drive expression of a predicted constitutively active form of Rab10 that is tagged at the N-terminal end with YFP.

(Zhang et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Rab10
Tagged with
YFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The co-expression of Rab10Q68L.Scer\UAS.P\T.T:Avic\GFP-YFP does not suppress the basement membrane deposition defects observed in follicle cells expressing stratGD10605 under the control of Scer\GAL4tj.PU.

      (Devergne et al., 2017)

      Co-expression of Rab10Q68L.Scer\UAS.P\T.T:Avic\GFP-YFP weakly suppresses the uninflated wing phenotype of Scer\GAL4Ccap.PP, OsbpScer\UAS.cMa flies.

      (Ma et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rab10Q68L.Scer\UAS.P\T.T:Avic\GFP-YFP
      Rab10Q68L.UASp.YFP
      Rab10Q68L
      (Bellec et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)