FB2025_01 , released February 20, 2025
Allele: Scer\GAL4NP0242
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General Information
Symbol
Scer\GAL4NP0242
Species
S. cerevisiae
Name
FlyBase ID
FBal0245089
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}NP0242
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}NP0242
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        adult stage
        mushroom body output neuron 6
        (Flybrain Neuron Database et al., 2018.6.28, Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body alpha' anterior-posterior layer
        (Tanaka et al., 2008)
        mushroom body alpha' lobe slice 1
        (Tanaka et al., 2008)
        mushroom body beta lobe posterior layer
        (Tanaka et al., 2008)
        mushroom body beta lobe surface layer
        (Tanaka et al., 2008)
        mushroom body beta lobe core layer
        (Tanaka et al., 2008)
        mushroom body beta lobe slice 1
        (Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body beta lobe slice 2
        (Shuai et al., 2015, Tanaka et al., 2008)
        adult brain | restricted
        (Shuai et al., 2015)
        mushroom body extrinsic neuron
        (Shuai et al., 2015)
        mushroom body alpha lobe slice 1
        (Shuai et al., 2015)
        mushroom body alpha lobe slice 2
        (Shuai et al., 2015)
        mushroom body alpha lobe slice 3
        (Shuai et al., 2015)
        alpha/beta surface Kenyon cell
        (Flybrain Neuron Database et al., 2018.6.28)
        alpha/beta posterior Kenyon cell
        (Flybrain Neuron Database et al., 2018.6.28)
        alpha/beta core Kenyon cell
        (Flybrain Neuron Database et al., 2018.6.28)
        Kenyon cell
        (Flybrain Neuron Database et al., 2018.6.28)
        Additional Information
        Statement
        Reference

        ScerGAL4NP0242 drives expression in mushroom body extrinsic neurons, including medial-vertical lobe arborizing neuron 2, that innervate mushroom body beta lobe slices 1 and 2, and mushroom body alpha lobe slices 1, 2, 3.

        (Shuai et al., 2015)

        Medial-vertical lobe arborizing neuron 2 arborisation within the beta lobe is within segment 1 and 2 of the posterior stratum, and within segment 1 of the middle and anterior strata.

        (Tanaka et al., 2008)
         
        Marker for
        mushroom body output neuron 6
        (Tanaka et al., 2008)
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4NP0242 neurons, in combination with a Gal80[ts] transgene to restrict expression to 1 day prior to training and testing, does not affect 3 hour aversive olfactory memory, compared to controls.

        (Shuai et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4NP0242
        Name Synonyms
        Secondary FlyBase IDs
          References (5)