FB2025_01 , released February 20, 2025
Allele: Dmel\EndoAUAS.cLa
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General Information
Symbol
Dmel\EndoAUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Li
FlyBase ID
FBal0264840
Feature type
allele
Associated gene
Dmel\EndoA
Associated Insertion(s)
Carried in Construct
P{UAS-EndoA.L}
Key Links
Transgenic product class
wild_type
(Li et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Li et al., 2010)
Mutagen
in vitro construct
(Li et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-EndoA.L}
Cytology
Description

UAS regulatory sequences drive expression of EndoA.

(Li et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
EndoA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL41032.hx/EndoAUAS.cLa is a non-suppressor of lethal | P-stage phenotype of Df(2L)TW119/BicDr5

      (Li et al., 2010)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of endoAScer\UAS.cLa under the control of Scer\GAL41032.hx partially suppresses the defects in larval locomotion of BicDr5/Df(2L)TW119 mutants, but it is insufficient to suppress lethality.

      The dye-release defects of BicDr5/Df(2L)TW119 mutants can be fully suppressed by presynaptic overexpression of endoAScer\UAS.cLa under the control of Scer\GAL4elav-C155.

      (Li et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      EndoAScer\UAS.cLa
      EndoAUAS.cLa
      endoAScer\UAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Li
      Secondary FlyBase IDs
        References (1)