FB2025_01 , released February 20, 2025
Allele: Dmel\Trx2+tSa
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General Information
Symbol
Dmel\Trx2+tSa
Species
D. melanogaster
Name
FlyBase ID
FBal0279423
Feature type
allele
Associated gene
Dmel\Trx2
Associated Insertion(s)
Carried in Construct
P{Trx2.S}
Key Links
Transgenic product class
genomic_DNA
(Svensson and Larsson, 2007)
wild_type
(Svensson and Larsson, 2007)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Svensson and Larsson, 2007)
wild_type
(Svensson and Larsson, 2007)
Mutagen
in vitro construct
(Svensson and Larsson, 2007)
Progenitor genotype
Carried in construct
P{Trx2.S}
Cytology
Description

Genomic fragment containing Trx-2.

(Svensson and Larsson, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Trx2
Encoded product / tool
Trx2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying three copies of Trx-2+tSa show increased tolerance to oxidative stress compared to controls.

      (Svensson and Larsson, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Trx2+tSa rescues Trx26

      (Svensson and Larsson, 2007)
      Comments

      Trx-2+tSa rescues the shortened lifespan of Trx-26 homozygotes.

      (Svensson and Larsson, 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Trx-2+tSa
      Trx2+tSa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)