FB2025_01 , released February 20, 2025
Allele: Dmel\Gyc76CΔPBM.UAS.Tag:MYC
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General Information
Symbol
Dmel\Gyc76CΔPBM.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0319248
Feature type
allele
Associated gene
Dmel\Gyc76C
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-Gyc76C.ΔPBM}
Key Links
Transgenic product class
inframe_deletion
(Chak and Kolodkin, 2014)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Chak and Kolodkin, 2014)
Mutagen
in vitro construct
(Chak and Kolodkin, 2014)
Progenitor genotype
Carried in construct
P{UAS-Myc-Gyc76C.ΔPBM}
Cytology
Description

UAS regulatory sequences drive expression of Gyc76C which lacks the PDZ binding motif (amino acids 1522-1525 are deleted). The endogenous signal peptide sequence has been replaced by a Igk-leader sequence followed by 5 copies of the Tag:MYC tag.

(Chak and Kolodkin, 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Gyc76C
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4elav.PU/Gyc76CΔPBM.UAS.Tag:MYC fails to rescue Gyc76CKG03723ex173

      (Chak and Kolodkin, 2014)
      Comments

      Expression of Gyc76CΔPBM.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav.PU fails to rescue the ISNb and SNa motor neuron axon pathway phenotypes of Gyc76CKG03723ex173/Gyc76CKG03723ex173 embryos.

      (Chak and Kolodkin, 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gyc76CΔPBM.Scer\UAS.T:Hsap\MYC
      Gyc76CΔPBM.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)